High-content, arrayed compound screens with rhinovirus, influenza A virus and herpes simplex virus infections

Dominik Olszewski; Fanny Georgi; Luca Murer; Vardan Andriasyan; Fabien Kuttler; Anthony Petkidis; Robert Witte; Artur Yakimovich; Lucy Fischer; Alina Rozanova; Yohei Yamauchi; Gerardo Turcatti; Urs F. Greber

doi:10.1038/s41597-022-01733-4

Scientific Data (Oct 2022)

High-content, arrayed compound screens with rhinovirus, influenza A virus and herpes simplex virus infections

Dominik Olszewski,
Fanny Georgi,
Luca Murer,
Vardan Andriasyan,
Fabien Kuttler,
Anthony Petkidis,
Robert Witte,
Artur Yakimovich,
Lucy Fischer,
Alina Rozanova,
Yohei Yamauchi,
Gerardo Turcatti,
Urs F. Greber

Affiliations

Dominik Olszewski: Department of Molecular Life Sciences, University of Zurich (UZH)
Fanny Georgi: Department of Molecular Life Sciences, University of Zurich (UZH)
Luca Murer: Department of Molecular Life Sciences, University of Zurich (UZH)
Vardan Andriasyan: Department of Molecular Life Sciences, University of Zurich (UZH)
Fabien Kuttler: Biomolecular Screening Facility, School of Life Sciences, Ecole Polytechnique Fédérale (EPFL) de Lausanne
Anthony Petkidis: Department of Molecular Life Sciences, University of Zurich (UZH)
Robert Witte: Department of Molecular Life Sciences, University of Zurich (UZH)
Artur Yakimovich: Center for Advanced Systems Understanding (CASUS), Helmholtz Center Dresden-Rossendorf
Lucy Fischer: Department of Molecular Life Sciences, University of Zurich (UZH)
Alina Rozanova: Department of Molecular Life Sciences, University of Zurich (UZH)
Yohei Yamauchi: University of Bristol
Gerardo Turcatti: Biomolecular Screening Facility, School of Life Sciences, Ecole Polytechnique Fédérale (EPFL) de Lausanne
Urs F. Greber: Department of Molecular Life Sciences, University of Zurich (UZH)

DOI: https://doi.org/10.1038/s41597-022-01733-4
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 12

Abstract

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Measurement(s) transmission of virus • drug toxicity Technology Type(s) fluorescence microscopy Factor Type(s) virus genotype • cell line • incubation temperature • number of cells seeded/ seeding density • inoculation time • virus input FFU • drug concentration Sample Characteristic - Organism Homo sapiens • Rhinovirus A • Influenza A virus • Human alphaherpesvirus 1 Sample Characteristic - Environment epithelium Sample Characteristic - Location Switzerland

Published in Scientific Data

ISSN: 2052-4463 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/sdata/

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