Качественная клиническая практика (May 2018)
Clinical and pharmacoeconomic aspects of anti-TNF therapy change for medical reasons
Abstract
The substitution of one drug for another within one class can be caused by both medical indications, such as low therapeutic efficacy, and by non-medical factors, for example, by choosing a less expensive drug. In this article, the available data on the impact of non-medical switching on the clinical and pharmacoeconomic indices of anti-TNF therapy with drugs are considered.