MODERN ALGORITHMS OF MICROBIOLOGICAL DIAGNOSTICS OF TUBERCULOSIS

Abstract

The article presents the comparative analysis of the microbiological diagnostics algorithm, developed and used in Central Tuberculosis Research Institute and the algorithm of laboratory diagnostics and monitoring of treatment of pulmonary tuberculosis and drug resistant tuberculosis based on modern rapid molecular techniques, developed by the experts of European Laboratory Initiatives jointly with Secretariat of Regional Office for Europe of World Health Organisation (WHO) for countries of the WHO European Region.It has been proved that despite some differences in these algorithms, the main principles on which they are based and approaches to diagnostics are similar. In both cases, molecular diagnostic tests and culture on liquid media are preferable for primary diagnostics in all suspected cases of tuberculosis. It provides rapid and accurate diagnostics and early detection of drug resistant tuberculosis, which finally enhances treatment efficiency and reduces transmission of tuberculosis

Keywords

• алгоритм микробиологической диагностики туберкулеза
• быстрые молекулярные тесты