Frontiers in Public Health (Mar 2023)

Comparison of newly diagnosed COPD patients and the non-COPD residents in Shanghai Minhang District

  • Xin Yin,
  • Zixuan Zheng,
  • Zixuan Zheng,
  • Yue Dong,
  • Yue Dong,
  • Yue Dong,
  • Junqing Li,
  • Junqing Li,
  • Shuang Yang,
  • Shuang Yang,
  • Qian Xu,
  • Shanshan Hou,
  • Yi Zang,
  • Heyuan Ding,
  • Juan Xie,
  • Juan Xie,
  • Zhijun Jie,
  • Zhijun Jie,
  • Qingwu Jiang,
  • Jindong Shi,
  • Jindong Shi,
  • Na Wang

DOI
https://doi.org/10.3389/fpubh.2023.1102509
Journal volume & issue
Vol. 11

Abstract

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BackgroundTo compare whether the general population, especially those without characteristic symptoms, need spirometry screening for chronic obstructive pulmonary disease (COPD).MethodsResidents aged > 40 years old in Minhang, Shanghai, China, filled out screening questionnaires and underwent spirometry. The structured questionnaire integrating COPD population screening and COPD screening questionnaire was designed to obtain data on demographic characteristics, risk factors of COPD, respiratory symptoms, lifestyle habits, and comorbidities. We assessed the correlations between variables and COPD and the impact factors of FEV1% predicted.ResultsA total of 1,147 residents were included with a newly diagnosed mild to moderate COPD prevalence of 9.4% (108/1,147); half of the patients (54/108) were asymptomatic. Multivariate analysis did not reveal any significant differences in symptoms or lifestyle factors between newly diagnosed COPD patients and non-COPD participants. However, according to the generalized linear model, older age (β = −0.062, p < 0.001), male sex (β = −0.031, p = 0.047), and respiratory symptoms (β = −0.025, p = 0.013) were associated with more severe airflow limitation.ConclusionNewly diagnosed COPD patients had few differences compared with the general population, which suggests that a targeted case finding strategy other than general screening was currently preferred. More attention should be paid to respiratory symptoms when making a diagnosis and exploring new therapies and interventions for COPD in the early stage.

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