Communications Biology (Jun 2022)

Spontaneous pauses in firing of external pallidum neurons are associated with exploratory behavior

  • Alexander Kaplan,
  • Aviv D. Mizrahi-Kliger,
  • Pnina Rappel,
  • Liliya Iskhakova,
  • Gennadiy Fonar,
  • Zvi Israel,
  • Hagai Bergman

DOI
https://doi.org/10.1038/s42003-022-03553-z
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 6

Abstract

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Integrated analysis of external pallidum (GPe) neuronal firing, pupil size, and saccadic movements in non-human primates reveals that pauses in GPe firing are associated with pupil dilation. These results suggest that pauses in GPe activity might influence downstream structures in the basal ganglia network and influence exploratory behavior.