Chemistry (May 2024)

Biological Applications of Thiourea Derivatives: Detailed Review

  • Fatimah A. Agili

DOI
https://doi.org/10.3390/chemistry6030025
Journal volume & issue
Vol. 6, no. 3
pp. 435 – 468

Abstract

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Thiourea and its derivatives have become a significant focal point within the organic synthesis field, garnering attention for their diverse biological applications, including antibacterial, antioxidant, anticancer, anti-inflammatory, anti-Alzheimer, antituberculosis and antimalarial properties. My objective is to present a comprehensive and easily understandable analysis of recent advancements in the organic synthesis of thiourea derivatives. My focus is on the structure and activity of these derivatives over the past five years, highlighting the significant progress made in the field of organic synthesis. Additionally, I evaluate the current state of research in this area and provide an overview of the latest trends and future prospects. This review will prove to be beneficial for researchers, academics and industry professionals involved in drug development and organic synthesis.

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