Does roflumilast induce phagocytic activity in COPD patients?

Abstract

Baishakhi Ghosh,1,2 Nitin V Vanjare1 1Chest Research Foundation (CRF), Pune, Maharashtra, India; 2Faculty of Health and Biomedical Science (FOHBS), Symbiosis International University, Pune, Maharashtra, IndiaWe read the article by Porpodis et al1 with great interest. In this study, the authors have evaluated the effect of roflumilast on the phagocytic activity of systemic phagocytes in severe and very severe COPD patients by measuring the oxidative burst post-bacterial stimulation. The study group for this study involved 21 severe or very severe COPD patients who were administered roflumilast in addition to other COPD treatments such as long-acting beta-adrenoceptor agonists (LABA) + inhaled corticosteroids (ICS) + long-acting anti-muscarinic agent (LAMA) or ICS + LABA.View original paper by Porpodis and colleagues.