Indian Journal of Pathology and Microbiology (Jan 2018)

Orchitis: An unusual presentation of polyarteritis nodosa

  • Nelofar Islam,
  • Debanjali Sinha,
  • Parasar Ghosh,
  • Chhanda Datta,
  • Uttara Chatterjee

DOI
https://doi.org/10.4103/IJPM.IJPM_569_17
Journal volume & issue
Vol. 61, no. 4
pp. 600 – 603

Abstract

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Polyarteritis nodosa (PAN), a systemic necrotizing vasculitis with multiorgan development, is generally restricted to the medium-sized muscular arteries. The varied initial clinical presentations of PAN can lead to a delayed diagnosis. We present the case of a middle-aged male patient who presented with an acute onset right-sided testicular pain as the initial clinical symptom with ischemic changes on ultrasonogram, thereby requiring orchiectomy. This was reported to be a case of tubercular epididymo-orchitis. On review, the biopsy revealed features of necrotizing arteritis as seen in PAN with fibrinoid necrosis and giant cells, thus highlighting the fact that vasculitis due to PAN may have a localized presentation at the time of diagnosis. PAN should be distinguished from other causes of epididymo-orchitis and other vasculitis lesions, the most common being tubercular etiology in the Asian population.

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