Nature Communications (Nov 2020)

Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin

  • Beatrice Dyring-Andersen,
  • Marianne Bengtson Løvendorf,
  • Fabian Coscia,
  • Alberto Santos,
  • Line Bruun Pilgaard Møller,
  • Ana R. Colaço,
  • Lili Niu,
  • Michael Bzorek,
  • Sophia Doll,
  • Jørgen Lock Andersen,
  • Rachael A. Clark,
  • Lone Skov,
  • Marcel B. M. Teunissen,
  • Matthias Mann

DOI
https://doi.org/10.1038/s41467-020-19383-8
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 14

Abstract

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The human skin is a highly complex organ comprising multiple tissue layers and diverse cell types. Here, the authors present a spatially-resolved quantitative proteomic atlas of the healthy human skin, characterizing the protein profiles of four skin layers and nine cell types.