Frontiers in Physiology (Dec 2017)
Corrigendum: Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment
- Sara Dutta,
- Kelly C. Chang,
- Kylie A. Beattie,
- Jiansong Sheng,
- Phu N. Tran,
- Wendy W. Wu,
- Min Wu,
- David G. Strauss,
- Thomas Colatsky,
- Zhihua Li
Affiliations
- Sara Dutta
- Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States
- Kelly C. Chang
- Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States
- Kylie A. Beattie
- Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States
- Jiansong Sheng
- Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States
- Phu N. Tran
- Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States
- Wendy W. Wu
- Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States
- Min Wu
- Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States
- David G. Strauss
- Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States
- Thomas Colatsky
- Marshview Life Science Advisors, Seabrook Island, SC, United States
- Zhihua Li
- Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States
- DOI
- https://doi.org/10.3389/fphys.2017.01025
- Journal volume & issue
-
Vol. 8
Abstract
No abstracts available.Keywords
- Torsade-de-Pointes (TdP)
- Comprehensive in vitro Proarrhythmia Assay (CiPA)
- rapid delayed rectifier potassium current (IKr)
- in silico cardiac cell model
- drug block
- proarrythmia risk