RNase III and RNase E Influence Posttranscriptional Regulatory Networks Involved in Virulence Factor Production, Metabolism, and Regulatory RNA Processing in Bordetella pertussis
Gyles Ifill,
Travis Blimkie,
Amy Huei-Yi Lee,
George A. Mackie,
Qing Chen,
Scott Stibitz,
Robert E. W. Hancock,
Rachel C. Fernandez
Affiliations
Gyles Ifill
Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada
Travis Blimkie
Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada
Amy Huei-Yi Lee
Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada
George A. Mackie
Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada
Qing Chen
Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA
Scott Stibitz
Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA
Noncoding, regulatory RNAs in bacterial pathogens are critical components required for rapid changes in gene expression profiles. However, little is known about the role of regulatory RNAs in the growth and pathogenesis of Bordetella pertussis