Recent advances in copper-catalyzed C–H bond amidation

Abstract

Copper catalysis has been known as a powerful tool for its ubiquitous application in organic synthesis. One of the fundamental utilities of copper catalysis is in the C–N bond formation by using carbon sources and nitrogen functional groups such as amides. In this review, the recent progress in the amidation reactions employing copper-catalyzed C–H amidation is summarized.

Keywords

• amidation
• C–H bond
• cascade reactions
• Copper catalysis
• intermolecular
• intramolecular