Rapid remodeling observed at mid-term in-vivo study of a smart reinforced acellular vascular graft implanted on a rat model

Abstract

Abstract Background The poor performance of conventional techniques used in cardiovascular disease patients requiring hemodialysis or arterial bypass grafting has prompted tissue engineers to search for clinically appropriate off-the-shelf vascular grafts. Most patients with cardiovascular disease lack suitable autologous tissue because of age or previous surgery. Commercially available vascular grafts with diameters of 1.5 years) in large animals with a vasculature similar to humans are needed.

Keywords

• Vascular graft
• Electrospinning
• Nanofibers
• Medium-term performance
• Tissue regeneration
• 3D printing