Repeat cross-sectional data on the progression of the metabolic syndrome in Ossabaw miniature swine
Mikaela L. McKenney-Drake,
Stacey D. Rodenbeck,
Meredith K. Owen,
Kyle A. Schultz,
Mouhamad Alloosh,
Johnathan D. Tune,
Michael Sturek
Affiliations
Mikaela L. McKenney-Drake
Department of Cellular & Integrative Physiology, Indiana University School of Medicine, 635 Barnhill Dr., Indianapolis, IN 46202, United States; College of Pharmacy & Health Sciences, Butler University, 4600 Sunset Avenue, Indianapolis, IN 46208, United States
Stacey D. Rodenbeck
Department of Cellular & Integrative Physiology, Indiana University School of Medicine, 635 Barnhill Dr., Indianapolis, IN 46202, United States
Meredith K. Owen
Department of Cellular & Integrative Physiology, Indiana University School of Medicine, 635 Barnhill Dr., Indianapolis, IN 46202, United States; Covance, Inc. 671 South Meridian Road, Greenfield, IN 46140, United States
Kyle A. Schultz
Department of Cellular & Integrative Physiology, Indiana University School of Medicine, 635 Barnhill Dr., Indianapolis, IN 46202, United States
Mouhamad Alloosh
Department of Cellular & Integrative Physiology, Indiana University School of Medicine, 635 Barnhill Dr., Indianapolis, IN 46202, United States
Johnathan D. Tune
Department of Cellular & Integrative Physiology, Indiana University School of Medicine, 635 Barnhill Dr., Indianapolis, IN 46202, United States
Michael Sturek
Department of Cellular & Integrative Physiology, Indiana University School of Medicine, 635 Barnhill Dr., Indianapolis, IN 46202, United States; Corresponding author. Phone: +1 317 274 7772; fax: +1 317 274 3318.
Ossabaw miniature swine were fed an excess calorie, atherogenic diet for 6, 9, or 12 months. Increased body weight, hypertension, and increased plasma cholesterol and triglycerides are described in Table 1. For more detailed interpretations and conclusions about the data, see our associated research study, “Biphasic alterations in coronary smooth muscle Ca2+ regulation during coronary artery disease progression in metabolic syndrome” McKenney-Drake, et al. (2016) [1].
