Reactive Chemical Gastropathy in PostLung Transplant Patient: A Rare Case Report

Abstract

Reactive chemical gastropathy is also termed drug-induced gastropathy. The terms gastropathy and gastritis vary in their etiology ultimately causing mucosal injury. The gastric mucosa is different in different regions. The oxyntic mucosa is seen in the body and fundus while antral mucosa is seen in the antrum and pyloric region. Antral mucosa bares G-cell which gives fried egg appearance on hematoxylin and eosin stain. The normal gastric mucosa is devoid of neutrophils outside vascular spaces. Most of the drugs used in modern medicine are often associated with adverse effects, especially in the gastrointestinal tract, and are mild but can be life-threatening. Here, we discuss a case of a 67-year-old male who had undergone a lung transplant in 2023, followed by reactive chemical gastropathy in 2024 with deposition of Kayexalate crystals in gastric mucosa while being treated for hyperkalemia which is a rare entity noticed in posttransplant patients.

Keywords

• gastropathy
• hyperkalemia
• kayexalate crystals
• transplant