Extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia

Abstract

Disseminated tuberculosis is an important differential diagnosis for fever of unknown origin (FUO) and it can present with hepatosplenomegaly and lymphadenopathy and may have meningitis and with hematological abnormalities including pancytopenia or a leukemoid reaction. We report the case of a 13-year old male who presented with fever, weight loss, pallor and massive splenomegaly with pancytopenia, in whom a bone marrow trephine biopsy showed caseating granulomata, who responded well to antituberculous treatment and has remained healthy on follow up after nine years.

Keywords

• FUO
• Tuberculosis
• Massive splenomegaly
• Pancytopenia
• Extrapulmonary
• Hypersplenism