Comprehensive review of membranoproliferative glomerulonephritis: spotlighting the latest advances in revised classification and treatment

Abstract

Membranoproliferative glomerulonephritis (MPGN) is a complex group of renal diseases characterized by a specific pattern of glomerular injury that includes thickening of the capillary wall and mesangial expansion, leading to a heterogeneous group of conditions. This review article offers a comprehensive overview of MPGN, its new classification, pathophysiology, diagnostic evaluation, and management options.

Keywords

• complement system proteins
• glomerulonephritis membranoproliferative
• immunoglobulins
• pediatrics