Reversible Altered Consciousness and Brain Atrophy Induced by Valproic Acid

Abstract

A 5-year-old female child with valproic acid (VPA)-related alteration of consciousness and brain atrophy that progressed over a 3 day period and resolved within 12 hours of discontinuing VPA is reported from Dokkyo University School of Medicine and Shimotsuga General Hospital, Tochigi, Japan.

Keywords

• valproic acid
• central focal spikes
• neurologic examination