Methods for degrading dicloxacillin in water using inorganic peroxides and their combination with UVC- experimental and theoretical aspects
Fidel Granda-Ramírez,
Efraím A. Serna-Galvis,
Yenny Ávila-Torres,
Ricardo A. Torres-Palma,
Gina Hincapié-Mejía
Affiliations
Fidel Granda-Ramírez
Grupo de Investigación Ambiente, Hábitat y Sostenibilidad, Facultad de Arquitectura e Ingeniería, Institución Universitaria Colegio Mayor de Antioquia, Carrera 78 No. 65-46, Medellín, Colombia
Efraím A. Serna-Galvis
Grupo de Investigación en Remediación Ambiental y Biocatálisis (GIRAB), Instituto de Química, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia; Grupo de Catalizadores y Adsorbentes (CATALAD), Instituto de Química, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia
Yenny Ávila-Torres
Grupo de Investigación en Remediación Ambiental y Biocatálisis (GIRAB), Instituto de Química, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia
Ricardo A. Torres-Palma
Grupo de Investigación en Remediación Ambiental y Biocatálisis (GIRAB), Instituto de Química, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia
Gina Hincapié-Mejía
Grupo de Investigación Ambiente, Hábitat y Sostenibilidad, Facultad de Arquitectura e Ingeniería, Institución Universitaria Colegio Mayor de Antioquia, Carrera 78 No. 65-46, Medellín, Colombia; Corresponding author.
Antibiotics are currently recognized as environmental pollutants. In this work, the methods involved in the degradation of a β-lactam antibiotic (i.e., DXC) by treatments based on inorganic peroxides and UVC (e.g., UVC alone, UV-C/H2O2, UVC/peroxymonosulfate, and UVC/peroxydisulfate) are presented. The methodology of computational calculations to obtain frontier orbitals and Fukui indices for DXC, and elucidate the reactive moieties on the target substance is also shown. Finally, the direct oxidation by peroxides and UV-C/H2O2 action to treat DXC in simulated pharmaceutical wastewater are depicted. The chromatographic and theoretical analyses allowed for determining the degrading performance of inorganic peroxides and UVC-based treatments toward the target pollutant in aqueous samples. • Treatments based on inorganic peroxides and UVC as useful methods for degrading the β-lactam antibiotic dicloxacillin. • Persulfates and UV-C/H2O2 showed high degrading action on the target pharmaceutical. • Methodologies based on theoretical calculations for the identification of reactive moieties on the DXC susceptible to radical attacks are presented.
