Trends in Mortality from Stroke in Latin America and the Caribbean, 1979–2015
Álvaro Soto,
Francisco Guillén-Grima,
Gladys Morales,
Sergio Muñoz,
Inés Aguinaga-Ontoso,
Jairo Vanegas
Affiliations
Álvaro Soto
Departamento de Especialidades Médicas, Facultad de Medicina, Universidad de La Frontera, Temuco; Unidad de Neurología. Hospital Dr. Hernán Henríquez Aravena, Temuco; Centro de Excelencia en Capacitación, Investigación y Gestión para la Salud Basada en Evidencia (CIGES), Facultad de Medicina, Universidad de La Frontera, Temuco; Centro de Investigación en Epidemiología Cardiovascular y Nutricional (EPICYN), Facultad de Medicina, Universidad de La Frontera, Temuco
Francisco Guillén-Grima
Departamento de Ciencias de la Salud, Universidad Pública de Navarra, Pamplona, Navarra; Instituto de Investigación Sanitaria de Navarra (IDISNA), Pamplona, Navarra; Medicina Preventiva, Clínica Universidad de Navarra, Pamplona, Navarra
Gladys Morales
Centro de Investigación en Epidemiología Cardiovascular y Nutricional (EPICYN), Facultad de Medicina, Universidad de La Frontera, Temuco; Departamento de Salud Pública, Facultad de Medicina, Universidad de La Frontera, Temuco
Sergio Muñoz
Centro de Excelencia en Capacitación, Investigación y Gestión para la Salud Basada en Evidencia (CIGES), Facultad de Medicina, Universidad de La Frontera, Temuco; Centro de Investigación en Epidemiología Cardiovascular y Nutricional (EPICYN), Facultad de Medicina, Universidad de La Frontera, Temuco; Departamento de Salud Pública, Facultad de Medicina, Universidad de La Frontera, Temuco
Inés Aguinaga-Ontoso
Departamento de Ciencias de la Salud, Universidad Pública de Navarra, Pamplona, Navarra; Instituto de Investigación Sanitaria de Navarra (IDISNA), Pamplona, Navarra
Jairo Vanegas
Facultad de Ciencias Médicas, Departamento de Salud Pública. Universidad de Santiago de Chile
Background: Stroke is the second largest single cause of death and disability in Latin America and the Caribbean (LAC). There have been large overall declines in stroke mortality rates in most LAC countries in recent decades. Objective: To analyze trends in mortality caused by stroke in LAC countries in the period 1979–2015. Methods: We extracted data for age-standardized stroke mortality rates per 100,000 in LAC for the period 1979–2015 from the World Health Organization Mortality Database. Joinpoint regression was used to analyze the trends and compute the annual percent change (APC) in LAC as a whole and by country. Analyses were conducted by gender, region and World Bank income classification. Results: Mortality from stroke has decreased in LAC over the study period by an average APC of –1.9%. Most countries showed significant downward trends, with the sharpest decreases in Chile, Colombia and Uruguay. We recorded statistically significant decreases of –1.4% and –2.4% in mortality rates in men and women, respectively, in the whole LAC. Southern and high-income countries showed the steepest decreases. Conclusions: Stroke mortality has decreased in LAC, in both sexes, especially in southern and high-income countries. Our results could serve as a reference for the development of primary prevention and acute management of stroke policies focused on countries with higher mortality.