European Clinical Respiratory Journal (Jan 2020)

Guideline for the management of COVID-19 patients during hospital admission in a non-intensive care setting

  • Klaus Nielsen Jeschke,
  • Barbara Bonnesen,
  • Ejvind Frausing Hansen,
  • Jens-Ulrik Stæhr Jensen,
  • Therese Sophie Lapperre,
  • Ulla Møller Weinreich,
  • Ole Hilberg

DOI
https://doi.org/10.1080/20018525.2020.1761677
Journal volume & issue
Vol. 7, no. 1

Abstract

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Introduction Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has presented health-care systems worldwide with novel challenges and experiences and evidence is emerging during the pandemic. Patients requiring hospitalization frequently suffer from respiratory failure of different severities. Aim The aim of this guideline is the treatment of patients with SARS CoV-2 (COVID-19) in hospital; in particular, it addresses the treatment of respiratory failure treated in general Internal Medical- and Pulmonary Medical wards. Results Elderly patients and patients with chronic disease are particularly vulnerable to COVID-19. Target oxygen saturation should be between 92% and 96% in patients without chronic lung diseases. Treatment with >5 L oxygen/min should be in close collaboration with intensive care colleagues and >15 l/min preferably in intensive care units. High-flow nasal canula (HFNC) and long-term Continuous Positive Airway Pressure (CPAP) are recommended for patients not responding to conventional oxygen therapy. Non-invasive ventilation (NIV) is only recommended for selected patients, such as those with a ceiling of treatment or patients presenting with hypercapnic failure. With the use of humidification protective equipment as FFP2-3 masks should be used. Nebulized medication should be avoided, and spacers should be used instead. Conclusion Respiratory failure is frequently the cause of hospitalization in patients with COVID-19 and should be monitored closely.

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