Neurofibromatosis, Down's syndrome, and acquired abnormalities

Abstract

We report a patient with Down's syndrome and neurofibromatosis who presented with a keloid, sebaceous cyst and acanthosis nigricans, along with dental and ophthalmological defects. The coexistence of neurofibromatosis type 1 and Down's syndrome which are two unrelated genetic conditions is itself a rarity.

Keywords

• Acanthosis nigricans, Down's syndrome, keloid, myopia, neurofibromatosis, sebaceous cyst