579-C Reinvigoration of progenitor-exhausted CD8 T cells by anti-CTLA-4 contributes to the sustained activity of combination checkpoint blockade

• Xiaowei Xu,
• Wei Xu,
• Alexander Huang,
• Jeffrey Weber,
• Andy Minn,
• Kevin Wang,
• Tara Mitchell,
• Sasikanth Manne,
• Divij Mathew,
• E John Wherry,
• Daniel Tenney,
• Paulina Coutifaris,
• David Brocks,
• Sabrina Solis,
• Nicholas Han,
• Evgeny Kiner,
• Chirag Sachar,
• Sangeeth George,
• Patrick Yan,
• Melanie W Kiner,
• Amy I Laughlin,
• Shawn Kothari,
• Josephine R Giles,
• Rheem Ghinnagow,
• Cecile Alanio,
• Ahron Flowers,
• Ravi K Amaravadi,
• Giorgos C Karakousis,
• Lynn M Schuchter,
• Marcus Buggert,
• Ramin S Herati

Affiliations

Xiaowei Xu

1University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Wei Xu

1University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Alexander Huang

9University of Pennsylvania, Philadelphia, PA, USA

Jeffrey Weber

14NYU Langone Medical Center, New York, NY, USA

Andy Minn

1University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Kevin Wang

1University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Tara Mitchell

11Abramson Cancer Center, Philadelphia, PA, USA

Sasikanth Manne

1University of Pennsylvania, Philadelphia, PA, USA

Divij Mathew

9University of Pennsylvania, Philadelphia, PA, USA

E John Wherry

1University of Pennsylvania, Philadelphia, PA, USA

Daniel Tenney

12Bristol Myers Squibb, Princeton, NJ, USA

Paulina Coutifaris

1University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

David Brocks

2Immunai Inc., New York, N, USA Y

Sabrina Solis

3New York University Grossman School of Medicine, New York, NY, USA

Nicholas Han

1University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Evgeny Kiner

2Immunai Inc., New York, N, USA Y

Chirag Sachar

2Immunai Inc., New York, N, USA Y

Sangeeth George

4Bristol Myers Squibb Co Cambridge, Cambridge, MA, USA

Patrick Yan

5Stanford University, Stanford, CA, USA

Melanie W Kiner

6Icahn School of Medicine at Mount Sinai, New York, NY, USA

Amy I Laughlin

7Orlando Health Cancer Institute, Orlando, FL, USA

Shawn Kothari

8Winship Cancer Institute of Emory University, Atlanta, GA, USA

Josephine R Giles

9University of Pennsylvania, Philadelphia, PA, USA

Rheem Ghinnagow

1University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Cecile Alanio

10Institut Curie, Paris, Île-de-France, France

Ahron Flowers

11Abramson Cancer Center, Philadelphia, PA, USA

Ravi K Amaravadi

1University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Giorgos C Karakousis

1University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Lynn M Schuchter

11Abramson Cancer Center, Philadelphia, PA, USA

Marcus Buggert

13Karolinska Institute, Solna, Sweden

Ramin S Herati

3New York University Grossman School of Medicine, New York, NY, USA