709 Exosome surface display of IL-12 results in tumor-retained pharmacology with superior potency and limited systemic exposure

• Michael Doherty,
• Ke Xu,
• Tong Zi,
• Sriram Sathyanaryanan,
• Nuruddeen Lewis,
• Chang Ling Sia,
• Katherine Kirwin,
• Sonya Haupt,
• Gauri Mahimkar,
• Kevin Dooley,
• Su Chul Jang,
• Bryan Choi,
• Andrew Grube,
• Christine McCoy,
• Jorge Sanchez-Salazar,
• Scott Estes,
• Kyriakos Economides,
• Douglas Williams

Affiliations

Michael Doherty

Academic Rheumatology, University of Nottingham, Nottingham, UK

Ke Xu

Codiak BiSciences, Andover, MA, USA

Tong Zi

Codiak BiSciences, Andover, MA, USA

Sriram Sathyanaryanan

Codiak BiSciences, Andover, MA, USA

Nuruddeen Lewis

Codiak BiSciences, Andover, MA, USA

Chang Ling Sia

Codiak BiSciences, Andover, MA, USA

Katherine Kirwin

Codiak BiSciences, Andover, MA, USA

Sonya Haupt

Codiak BiSciences, Andover, MA, USA

Gauri Mahimkar

Codiak BiSciences, Andover, MA, USA

Kevin Dooley

Codiak BiSciences, Andover, MA, USA

Su Chul Jang

Codiak BiSciences, Andover, MA, USA

Bryan Choi

Codiak BiSciences, Andover, MA, USA

Andrew Grube

Codiak BiSciences, Andover, MA, USA

Christine McCoy

Codiak BiSciences, Andover, MA, USA

Jorge Sanchez-Salazar

Codiak BiSciences, Andover, MA, USA

Scott Estes

Codiak BiSciences, Andover, MA, USA

Kyriakos Economides

Codiak BiSciences, Andover, MA, USA

Douglas Williams

Codiak BiSciences, Andover, MA, USA