Two Successful Deliveries after 6 and 13 Years from 10 Oocytes Vitrified for Fertility Preservation in a Then 20-Year-Old Patient with PH-Positive Acute Lymphoid Leukemia

Yusuke Nakamura; Hiromitsu Hattori; Yukiko Nakajo; Noriyuki Okuyama; Nobuya Aono; Yuya Takeshige; Eri Sakamoto; Kanako Sato; Momoe Ota; Masae Koizumi; Mayumi Toya; Hideki Igarashi; Tomoko Hashimoto; Koichi Kyono

doi:10.1142/S2661318220500140

Fertility & Reproduction (Sep 2020)

Two Successful Deliveries after 6 and 13 Years from 10 Oocytes Vitrified for Fertility Preservation in a Then 20-Year-Old Patient with PH-Positive Acute Lymphoid Leukemia

Yusuke Nakamura,
Hiromitsu Hattori,
Yukiko Nakajo,
Noriyuki Okuyama,
Nobuya Aono,
Yuya Takeshige,
Eri Sakamoto,
Kanako Sato,
Momoe Ota,
Masae Koizumi,
Mayumi Toya,
Hideki Igarashi,
Tomoko Hashimoto,
Koichi Kyono

Affiliations

Yusuke Nakamura: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan
Hiromitsu Hattori: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan
Yukiko Nakajo: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan
Noriyuki Okuyama: Kyono ART Clinic Takanawa, Takanawa Court 5F, 3-13-1 Takanawa, Minato-ku, Tokyo 108-0074, Japan
Nobuya Aono: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan
Yuya Takeshige: Kyono ART Clinic Takanawa, Takanawa Court 5F, 3-13-1 Takanawa, Minato-ku, Tokyo 108-0074, Japan
Eri Sakamoto: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan
Kanako Sato: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan
Momoe Ota: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan
Masae Koizumi: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan
Mayumi Toya: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan
Hideki Igarashi: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan
Tomoko Hashimoto: Kyono ART Clinic Takanawa, Takanawa Court 5F, 3-13-1 Takanawa, Minato-ku, Tokyo 108-0074, Japan
Koichi Kyono: Kyono ART Clinic Sendai, 1-1-1-3F Honcho, Aoba-ku, Sendai, Miyagi 980-0014, Japan

DOI: https://doi.org/10.1142/S2661318220500140
Journal volume & issue: Vol. 2, no. 3
pp. 93 – 95

Abstract

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Oocyte vitrification is one of the methods for preserving fertility of cancer patients. In 2013, we reported a successful live birth using cryopreserved oocytes from a patient who contracted Ph-positive acute lymphoid leukemia at the retrieval age of 20. In this report, we described a second live birth from the same patient. The patient visited our clinic in November 2018 hoping to utilize vitrified oocytes cryopreserved in 2007. As a result, a day 3 single eight-cell stage embryo was transferred in a hormone replacement therapy cycle. She became pregnant and gave birth to a healthy girl (2,740 g) in September 2019. This is a case report of two live births from 10 matured oocytes that had been preserved for 12 years.

Published in Fertility & Reproduction

ISSN: 2661-3182 (Print); 2661-3174 (Online)
Publisher: World Scientific Publishing
Country of publisher: Singapore
LCC subjects: Science: Biology (General): Reproduction
Website: https://www.worldscientific.com/worldscinet/fandr

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