Ustekinumab-Induced Fatal Acute Heart Failure in a Young Female: A Case Report

Abstract

Data regarding short- and long-term cardiovascular complications of biological agents is lacking. Herein, the authors reported a case of abrupt onset of acute heart failure induced by ustekinumab treatment for resistant pityriasis rubra pilaris in a young healthy female with no past cardiac history. Although medical management was immediately initiated for cardiogenic shock, the patient passed away.

Keywords

• acute heart failure
• ustekinumab
• pityriasis rubra pilaris
• biological agents