Preparation and identification of some new thiazolidine -4-one compounds from Schiff base derivatives

Abstract

In this Study the two compounds ( 1 , 2 ) ( 5-styryl - 1,3,4- oxadiazol - 2-amine and 5-styryl - 1,3,4- thiadiazol - 2-amine ) were prepared by the reaction between ( cinammic acid ) and with of all semicarbazide , thiosemicarbazide in the middle of concentrated sulfuric acid , Then schiff bases ( 3 - 10 ) have been Prepared via by the condensation of compound ( 1 , 2 ) and the benzaldehyde dervatives ( 4-chlorobenzaldehyde , 2-chloro benzaldehyde , 4-nitro benzaldehyde , 2,4-dimethoxy benzaldehyde , 4-dimethylamino benzaldehyde ) . Finally , the new compounds ( thiazolidin-4-one ) ( 11 - 18 ) Five heterocyclic rings were prepared by the reaction of (thioglycholic acid) with Schiff bases . The synthesized compounds are identified by physical such as ( melting point , color change ) and spectral method such as ( IR , 1H - NMR ) .

Keywords

• schiff bases,,
• ,،,؛thiazolidine -4-one,,
• ,،,؛oxadiazole,,
• ,،,؛thiadiazole