Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3

Elham Jalalvand; Brita Robertson; Peter Wallén; Sten Grillner

doi:10.1038/ncomms10002

Nature Communications (Jan 2016)

Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3

Elham Jalalvand,
Brita Robertson,
Peter Wallén,
Sten Grillner

Affiliations

Elham Jalalvand: Department of Neuroscience, The Nobel Institute for Neurophysiology, Karolinska Institutet
Brita Robertson: Department of Neuroscience, The Nobel Institute for Neurophysiology, Karolinska Institutet
Peter Wallén: Department of Neuroscience, The Nobel Institute for Neurophysiology, Karolinska Institutet
Sten Grillner: Department of Neuroscience, The Nobel Institute for Neurophysiology, Karolinska Institutet

DOI: https://doi.org/10.1038/ncomms10002
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 12

Abstract

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Cerebrospinal fluid-contacting (CSF-c) cells line the central canal of the vertebrate spinal cord yet their function remains unknown. Here, Javaland et al. show that CSF-c neurons in the lamprey respond to mechanical stimulation and lowered pH, effects likely mediated by ASIC3-channels.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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