Emerging Infectious Diseases (Sep 2022)

Trichodysplasia Spinulosa Polyomavirus Endothelial Infection, California, USA

  • Lauren Lawrence,
  • Aihui Wang,
  • Gregory Charville,
  • Angus Toland,
  • Benjamin Pinsky,
  • Yasodha Natkunam,
  • Sheren Younes,
  • Henning Stehr,
  • Dita Gratzinger

DOI
https://doi.org/10.3201/eid2809.220856
Journal volume & issue
Vol. 28, no. 9
pp. 1935 – 1937

Abstract

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We describe 3 patients in California, USA, with trichodysplasia spinulosa polyomavirus (TSPyV) infection of endothelium after steroid administration. We detected TSPyV RNA in tissue specimens by in situ hybridization, which revealed localization to endothelial cells. These cases suggest that diseases associated with endothelial inflammation could be associated with TSPyV infection.

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