99 Structural optimization of anti-CEA-GITR-CAR to reduce tonic signaling and improve antigen-specific reactivity

• Hiroshi Shiku,
• Yizheng Wang,
• Linan Wang,
• Takuma Kato

Affiliations

Hiroshi Shiku

Aff1 grid.260026.0000000040372555XDepartment of Immuno-Gene TherapyMie University Graduate School of medicine Tsu Japan

Yizheng Wang

2Mie University Graduate School of Med., Tsu, Japan

Linan Wang

3Mie University, Tsu, Japan

Takuma Kato

2Mie University Graduate School of Med., Tsu, Japan