Archives of Pharmacy Practice (Sep 2011)
Phytochemical screening, anti-pyretic and antidiarrhoeal activities of the n-hexane and aqueous extracts of the leaves of Aegle marmelos
Abstract
Objective: The n-hexane and aqueous extracts of the leaves ofAegle marmelos have been examined anti-pyretic andantidiarrhoeal activities, and phytochemical screening.Materials and methods: Yeast-induced hyperthermia test wasused for antipyretic activity. For both the extracts, rectaltemperatures were measured at fixed intervals. Castor oilinduceddiarrhoea test was used for antidiarrhoeal activity. Forboth the extracts, the droppings were collected at fixedintervals. The phytochemical screening was done according tothe methods described in the literature.Result: The results indicated good anti-pyretic activity for theaqueous extract and good antidiarrhoeal activity for the nhexaneextract of Aegle marmelos.Conclusion: The results of the study supported the traditionaluse of plant as a crude anti-pyretic and antidiarrhoeal drug.