Nature Communications (Apr 2016)
ZBTB20 is required for anterior pituitary development and lactotrope specification
- Dongmei Cao,
- Xianhua Ma,
- Jiao Cai,
- Jing Luan,
- An-Jun Liu,
- Rui Yang,
- Yi Cao,
- Xiaotong Zhu,
- Hai Zhang,
- Yu-Xia Chen,
- Yuguang Shi,
- Guang-Xia Shi,
- Dajin Zou,
- Xuetao Cao,
- Michael J. Grusby,
- Zhifang Xie,
- Weiping J. Zhang
Affiliations
- Dongmei Cao
- Department of Pathophysiology, Second Military Medical University
- Xianhua Ma
- Department of Pathophysiology, Second Military Medical University
- Jiao Cai
- Department of Pathophysiology, Second Military Medical University
- Jing Luan
- Department of Pathophysiology, Second Military Medical University
- An-Jun Liu
- Department of Pathophysiology, Second Military Medical University
- Rui Yang
- Department of Pathophysiology, Second Military Medical University
- Yi Cao
- Department of Pathophysiology, Second Military Medical University
- Xiaotong Zhu
- Department of Pathophysiology, Second Military Medical University
- Hai Zhang
- Department of Pathophysiology, Second Military Medical University
- Yu-Xia Chen
- Department of Pathophysiology, Second Military Medical University
- Yuguang Shi
- Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio
- Guang-Xia Shi
- Department of Pathophysiology, Dalian Medical University, 9 West Section
- Dajin Zou
- Department of Endocrinology, Changhai Hospital
- Xuetao Cao
- National Key Laboratory of Molecular Biology and Department of Immunology, Chinese Academy of Medical Sciences
- Michael J. Grusby
- Department of Immunology and Infectious Diseases, Harvard School of Public Health
- Zhifang Xie
- Department of Pathophysiology, Second Military Medical University
- Weiping J. Zhang
- Department of Pathophysiology, Second Military Medical University
- DOI
- https://doi.org/10.1038/ncomms11121
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 13
Abstract
The pituitary is a complex structure with the anterior lobe containing five specialized cell types secreting different hormones. Here Cao et al. unravel a role for ZBTB20 in pituitary development and specifically in lactrotrope specification.
