Red-shifting mutation of light-driven sodium-pump rhodopsin

Keiichi Inoue; María del Carmen Marín; Sahoko Tomida; Ryoko Nakamura; Yuta Nakajima; Massimo Olivucci; Hideki Kandori

doi:10.1038/s41467-019-10000-x

Nature Communications (Apr 2019)

Red-shifting mutation of light-driven sodium-pump rhodopsin

Keiichi Inoue,
María del Carmen Marín,
Sahoko Tomida,
Ryoko Nakamura,
Yuta Nakajima,
Massimo Olivucci,
Hideki Kandori

Affiliations

Keiichi Inoue: Department of Life Science and Applied Chemistry, Nagoya Institute of Technology
María del Carmen Marín: Dipartimento di Biotecnologie, Chimica e Farmacia, Università di Siena
Sahoko Tomida: Department of Life Science and Applied Chemistry, Nagoya Institute of Technology
Ryoko Nakamura: Department of Life Science and Applied Chemistry, Nagoya Institute of Technology
Yuta Nakajima: Department of Life Science and Applied Chemistry, Nagoya Institute of Technology
Massimo Olivucci: Dipartimento di Biotecnologie, Chimica e Farmacia, Università di Siena
Hideki Kandori: Department of Life Science and Applied Chemistry, Nagoya Institute of Technology

DOI: https://doi.org/10.1038/s41467-019-10000-x
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 11

Abstract

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Microbial rhodopsins are photoreceptive and widely used in optogenetics for which they should preferable function with longer-wavelength light. Here, authors achieve a 40-nm red-shift in the absorption wavelength of a sodium-pump rhodopsin (KR2) by altering the distribution of the retinal chromophore.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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