Clinical and Translational Allergy (Jan 2023)
Digitally‐enabled, patient‐centred care in rhinitis and asthma multimorbidity: The ARIA‐MASK‐air® approach
- Jean Bousquet,
- Josep M. Anto,
- Bernardo Sousa‐Pinto,
- Wienczyslawa Czarlewski,
- Anna Bedbrook,
- Tari Haahtela,
- Ludger Klimek,
- Oliver Pfaar,
- Piotr Kuna,
- Maciej Kupczyk,
- Frederico S. Regateiro,
- Boleslaw Samolinski,
- Arunas Valiulis,
- Arzu Yorgancioglu,
- Sylvie Arnavielhe,
- Xavier Basagaña,
- Karl C. Bergmann,
- Sinthia Bosnic‐Anticevich,
- Luisa Brussino,
- G. Walter Canonica,
- Victoria Cardona,
- Lorenzo Cecchi,
- Claudia Chaves‐Loureiro,
- Elisio Costa,
- Alvaro A. Cruz,
- Bilun Gemicioglu,
- Wytske J. Fokkens,
- Juan Carlos Ivancevich,
- Helga Kraxner,
- Violeta Kvedariene,
- Désirée E. Larenas‐Linnemann,
- Daniel Laune,
- Renaud Louis,
- Michael Makris,
- Marcus Maurer,
- Erik Melén,
- Yann Micheli,
- Mario Morais‐Almeida,
- Joaquim Mullol,
- Marek Niedoszytko,
- Yoshitaka Okamoto,
- Nikolaos G. Papadopoulos,
- Vincenzo Patella,
- Nhân Pham‐Thi,
- Philip W. Rouadi,
- Joaquin Sastre,
- Nicola Scichilone,
- Aziz Sheikh,
- Mikhail Sofiev,
- Luis Taborda‐Barata,
- Sanna Toppila‐Salmi,
- Ioanna Tsiligianni,
- Erkka Valovirta,
- Maria Teresa Ventura,
- Rafael José Vieira,
- Mihaela Zidarn,
- Rita Amaral,
- Ignacio J. Ansotegui,
- Annabelle Bédard,
- Samuel Benveniste,
- Michael Bewick,
- Carsten Bindslev‐Jensen,
- Hubert Blain,
- Matteo Bonini,
- Rodolphe Bourret,
- Fulvio Braido,
- Pedro Carreiro‐Martins,
- Denis Charpin,
- Ivan Cherrez‐Ojeda,
- Tomas Chivato,
- Derek K. Chu,
- Cemal Cingi,
- Stefano DelGiacco,
- Frédéric deBlay,
- Philippe Devillier,
- Govert DeVries,
- Maria Doulaptsi,
- Virginie Doyen,
- Gérard Dray,
- Jean‐François Fontaine,
- R. Maximiliano Gomez,
- Jan Hagemann,
- Enrico Heffler,
- Maja Hofmann,
- Ewa Jassem,
- Marek Jutel,
- Thomas Keil,
- Vicky Kritikos,
- Inger Kull,
- Marek Kulus,
- Olga Lourenço,
- Eve Mathieu‐Dupas,
- Enrica Menditto,
- Ralph Mösges,
- Ruth Murray,
- Rachel Nadif,
- Hugo Neffen,
- Stefania Nicola,
- Robyn O’Hehir,
- Heidi Olze,
- Yuliia Palamarchuk,
- Jean‐Louis Pépin,
- Benoit Pétré,
- Robert Picard,
- Constantinos Pitsios,
- Francesca Puggioni,
- Santiago Quirce,
- Filip Raciborski,
- Sietze Reitsma,
- Nicolas Roche,
- Monica Rodriguez‐Gonzalez,
- Jan Romantowski,
- Ana Sá‐Sousa,
- Faradiba S. Serpa,
- Marine Savouré,
- Mohamed H. Shamji,
- Milan Sova,
- Annette Sperl,
- Cristiana Stellato,
- Ana Todo‐Bom,
- Peter Valentin Tomazic,
- Olivier Vandenplas,
- Michiel VanEerd,
- Tuula Vasankari,
- Frédéric Viart,
- Susan Waserman,
- Joao A. Fonseca,
- Torsten Zuberbier
Affiliations
- Jean Bousquet
- Institute of Allergology Charité – Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin Berlin Germany
- Josep M. Anto
- ISGlobal Barcelona Institute for Global Health Barcelona Spain
- Bernardo Sousa‐Pinto
- MEDCIDS ‐ Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto Porto Portugal
- Wienczyslawa Czarlewski
- Medical Consulting Czarlewski Levallois France
- Anna Bedbrook
- MASK‐air Montpellier France
- Tari Haahtela
- Skin and Allergy Hospital Helsinki University Hospital University of Helsinki Helsinki Finland
- Ludger Klimek
- Department of Otolaryngology, Head and Neck Surgery Universitätsmedizin Mainz Mainz Germany
- Oliver Pfaar
- Section of Rhinology and Allergy Department of Otorhinolaryngology, Head and Neck Surgery University Hospital Marburg Philipps‐Universität Marburg Marburg Germany
- Piotr Kuna
- Division of Internal Medicine, Asthma and Allergy Barlicki University Hospital Medical University of Lodz Lodz Poland
- Maciej Kupczyk
- Division of Internal Medicine, Asthma and Allergy Barlicki University Hospital Medical University of Lodz Lodz Poland
- Frederico S. Regateiro
- Allergy and Clinical Immunology Unit Centro Hospitalar e Universitário de Coimbra Coimbra Portugal
- Boleslaw Samolinski
- Department of Prevention of Environmental Hazards, Allergology and Immunology Medical University of Warsaw Warsaw Poland
- Arunas Valiulis
- Institute of Clinical Medicine and Institute of Health Sciences Vilnius Lithuania
- Arzu Yorgancioglu
- Department of Pulmonary Diseases Celal Bayar University, Faculty of Medicine Manisa Turkey
- Sylvie Arnavielhe
- GRADeS Occitanie Toulouse France
- Xavier Basagaña
- ISGlobal Barcelona Institute for Global Health Barcelona Spain
- Karl C. Bergmann
- Institute of Allergology Charité – Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin Berlin Germany
- Sinthia Bosnic‐Anticevich
- Quality Use of Respiratory Medicine Group Woolcock Institute of Medical Research The University of Sydney Sydney NSW Australia
- Luisa Brussino
- Department of Medical Sciences Allergy and Clinical Immunology Unit University of Torino Torino Italy
- G. Walter Canonica
- Department of Biomedical Sciences Humanitas University, Pieve Emanuele Milan Italy
- Victoria Cardona
- Allergy Section Department of Internal Medicine Hospital Vall d'Hebron Barcelona Spain
- Lorenzo Cecchi
- SOS Allergology and Clinical Immunology USL Toscana Centro Prato Italy
- Claudia Chaves‐Loureiro
- Pneumology Unit Hospitais da Universidade de Coimbra Centro Hospitalar e Universitário de Coimbra Coimbra Portugal
- Elisio Costa
- UCIBIO, REQUINTE Faculty of Pharmacy and Competence Center on Active and Healthy Ageing University of Porto (Porto4Ageing) Porto Portugal
- Alvaro A. Cruz
- Fundaçao ProAR Federal University of Bahia and GARD/WHO Planning Group Salvador Bahia Brazil
- Bilun Gemicioglu
- Cerrahpasa Faculty of Medicine Department of Pulmonary Diseases Istanbul University‐Cerrahpasa Istanbul Turkey
- Wytske J. Fokkens
- Department of Otorhinolaryngology Amsterdam University Medical Centres, location AMC Amsterdam the Netherlands
- Juan Carlos Ivancevich
- Servicio de Alergia e Immunologia Clinica Santa Isabel Buenos Aires Argentina
- Helga Kraxner
- Department of Otorhinolaryngology, Head and Neck Surgery Semmelweis University Budapest Hungary
- Violeta Kvedariene
- Faculty of Medicine Institute of Clinical Medicine Clinic of Chest Diseases and Allergology Vilnius University Vilnius Lithuania
- Désirée E. Larenas‐Linnemann
- Center of Excellence in Asthma and Allergy Médica Sur Clinical Foundation and Hospital México City Mexico
- Daniel Laune
- KYomed INNOV Montpellier France
- Renaud Louis
- Department of Pulmonary Medicine CHU Liege Liège Belgium
- Michael Makris
- Allergy Unit “D Kalogeromitros” 2nd Department of Dermatology and Venereology National & Kapodistrian University of Athens “Attikon” University Hospital Athens Greece
- Marcus Maurer
- Institute of Allergology Charité – Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin Berlin Germany
- Erik Melén
- Sach's Children and Youth Hospital Södersjukhuset Stockholm Sweden
- Yann Micheli
- KYomed INNOV Montpellier France
- Mario Morais‐Almeida
- Allergy Center CUF Descobertas Hospital Lisbon Portugal
- Joaquim Mullol
- Rhinology Unit & Smell Clinic ENT Department Hospital Clínic Barcelona Spain
- Marek Niedoszytko
- Department of Allergology Medical University of Gdańsk Gdansk Poland
- Yoshitaka Okamoto
- Chiba University Hospital Chiba Japan
- Nikolaos G. Papadopoulos
- Allergy Department 2nd Pediatric Clinic University of Athens Athens Greece
- Vincenzo Patella
- Division of Allergy and Clinical Immunology Department of Medicine “Santa Maria della Speranza” Hospital, Battipaglia Salerno Italy
- Nhân Pham‐Thi
- Ecole Polytechnique Palaiseau IRBA (Institut de Recherche Bio‐Médicale des Armées) Bretigny France
- Philip W. Rouadi
- Department of Otolaryngology, Head and Neck Surgery Eye and Ear University Hospital Beirut Lebanon
- Joaquin Sastre
- Fundacion Jimenez Diaz, CIBERES Faculty of Medicine Autonoma University of Madrid Madrid Spain
- Nicola Scichilone
- PROMISE Department University of Palermo Palermo Italy
- Aziz Sheikh
- Usher Institute The University of Edinburgh Edinburgh UK
- Mikhail Sofiev
- Finnish Meteorological Institute (FMI) Helsinki Finland
- Luis Taborda‐Barata
- Department of Immunoallergology Cova da Beira University Hospital Centre Covilhã Portugal
- Sanna Toppila‐Salmi
- Skin and Allergy Hospital Helsinki University Hospital University of Helsinki Helsinki Finland
- Ioanna Tsiligianni
- International Primary Care Respiratory Group IPCRG Aberdeen Scotland
- Erkka Valovirta
- Department of Lung Diseases and Clinical Immunology University of Turku Turku Finland
- Maria Teresa Ventura
- Unit of Geriatric Immunoallergology University of Bari Medical School Bari Italy
- Rafael José Vieira
- MEDCIDS ‐ Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto Porto Portugal
- Mihaela Zidarn
- University Clinic of Respiratory and Allergic Diseases Golnik Slovenia
- Rita Amaral
- MEDCIDS ‐ Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto Porto Portugal
- Ignacio J. Ansotegui
- Department of Allergy and Immunology Hospital Quironsalud Bizkaia Bilbao Spain
- Annabelle Bédard
- Inserm Equipe d’Epidémiologie Respiratoire Intégrative CESP Villejuif France
- Samuel Benveniste
- National Center of Expertise in Cognitive Stimulation (CEN STIMCO) Broca Hospital Paris France
- Michael Bewick
- University of Central Lancashire Medical School Preston UK
- Carsten Bindslev‐Jensen
- Odense Research Center for Anaphylaxis (ORCA) Odense Denmark
- Hubert Blain
- Department of Geriatrics Montpellier University Hospital, MUSE Montpellier France
- Matteo Bonini
- Department of Clinical and Surgical Sciences Fondazione Policlinico Universitario A Gemelli IRCCS Rome Italy
- Rodolphe Bourret
- Centre Hospitalier Valenciennes Valenciennes France
- Fulvio Braido
- Department of Internal Medicine (DiMI) University of Genoa Genova Italy
- Pedro Carreiro‐Martins
- NOVA Medical School/Comprehensive Health Research Centre (CHRC) Lisbon Portugal
- Denis Charpin
- Clinique des Bronches Allergie et Sommeil Hôpital Nord Marseille France
- Ivan Cherrez‐Ojeda
- Universidad Espíritu Santo Samborondón Ecuador
- Tomas Chivato
- School of Medicine University CEU San Pablo Madrid Spain
- Derek K. Chu
- Department of Health Research Methods, Evidence, and Impact & Department of Medicine McMaster University Hamilton ON Canada
- Cemal Cingi
- Medical Faculty ENT Department Eskisehir Osmangazi University Eskisehir Turkey
- Stefano DelGiacco
- Department of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology University Hospital “Duilio Casula” University of Cagliari Cagliari Italy
- Frédéric deBlay
- Allergy Division Chest Disease Department University Hospital of Strasbourg Strasbourg France
- Philippe Devillier
- VIM Suresnes, UMR 0892 Pôle des Maladies des Voies Respiratoires Hôpital Foch Université Paris‐Saclay Suresnes France
- Govert DeVries
- Peercode BV Geldermalsen The Netherlands
- Maria Doulaptsi
- Department of Otorhinolaryngology, Head and Neck Surgery University Hospital of Crete Heraklion, Crete Greece
- Virginie Doyen
- Department of Chest Medicine Centre Hospitalier Universitaire UCL Namur Namur Belgique
- Gérard Dray
- Ecole des Mines Alès France
- Jean‐François Fontaine
- Allergist Reims France
- R. Maximiliano Gomez
- School of Health Sciences Catholic University of Salta Salta Argentina
- Jan Hagemann
- Department of Otolaryngology, Head and Neck Surgery Universitätsmedizin Mainz Mainz Germany
- Enrico Heffler
- Department of Biomedical Sciences Humanitas University, Pieve Emanuele Milan Italy
- Maja Hofmann
- Institute of Allergology Charité – Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin Berlin Germany
- Ewa Jassem
- Department of Pneumology Medical University of Gdańsk Gdańsk Poland
- Marek Jutel
- Department of Clinical Immunology Wrocław Medical University Wrocław Poland
- Thomas Keil
- Institute of Social Medicine, Epidemiology and Health Economics Charité ‐ Universitätsmedizin Berlin Berlin Germany
- Vicky Kritikos
- Quality Use of Respiratory Medicine Group Woolcock Institute of Medical Research The University of Sydney Sydney NSW Australia
- Inger Kull
- Sach's Children and Youth Hospital Södersjukhuset Stockholm Sweden
- Marek Kulus
- Department of Pediatric Respiratory Diseases and Allergology Medical University of Warsaw Warsaw Poland
- Olga Lourenço
- Faculty of Health Sciences and CICS – UBI Health Sciences Research Centre University of Beira Interior Covilhã Portugal
- Eve Mathieu‐Dupas
- KYomed INNOV Montpellier France
- Enrica Menditto
- CIRFF Department of Pharmacy University of Naples Federico II Naples Italy
- Ralph Mösges
- CRI‐Clinical Research International‐Ltd Hamburg Germany
- Ruth Murray
- Medical Communication Consultant Medscript Ltd, Dundalk Ireland and Wellington New Zealand
- Rachel Nadif
- Inserm Equipe d’Epidémiologie Respiratoire Intégrative CESP Villejuif France
- Hugo Neffen
- Center of Allergy, Immunology and Respiratory Diseases Santa Fe Argentina
- Stefania Nicola
- Department of Medical Sciences Allergy and Clinical Immunology Unit University of Torino Torino Italy
- Robyn O’Hehir
- Department of Allergy, Immunology and Respiratory Medicine Alfred Hospital and Central Clinical School Monash University Melbourne Victoria Australia
- Heidi Olze
- Berlin Institute of Health Berlin Germany
- Yuliia Palamarchuk
- Finnish Meteorological Institute (FMI) Helsinki Finland
- Jean‐Louis Pépin
- Université Grenoble Alpes Laboratoire HP2 Grenoble France
- Benoit Pétré
- University of Liège Liège Belgium
- Robert Picard
- Conseil Général de l'Economie Ministère de l'Economie de l'Industrie et du Numérique Paris France
- Constantinos Pitsios
- Medical School University of Cyprus Nicosia Cyprus
- Francesca Puggioni
- Department of Biomedical Sciences Humanitas University, Pieve Emanuele Milan Italy
- Santiago Quirce
- Department of Allergy Hospital La Paz Institute for Health Research (IdiPAZ) Madrid Spain
- Filip Raciborski
- Department of Prevention of Environmental Hazards, Allergology and Immunology Medical University of Warsaw Warsaw Poland
- Sietze Reitsma
- Department of Otorhinolaryngology Amsterdam University Medical Centres, AMC Amsterdam the Netherlands
- Nicolas Roche
- Pneumologie AP‐HP Centre Université de Paris Cité Hôpital Cochin Paris France
- Monica Rodriguez‐Gonzalez
- Pediatric Allergy and Clinical Immunology Hospital Espanol de Mexico Mexico City Mexico
- Jan Romantowski
- Department of Allergology Medical University of Gdańsk Gdansk Poland
- Ana Sá‐Sousa
- MEDCIDS ‐ Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto Porto Portugal
- Faradiba S. Serpa
- Asthma Reference Center ‐ School of Medicine of Santa Casa de Misericórdia of Vitória Vitoria, Espirito Santo Brazil
- Marine Savouré
- Inserm Equipe d’Epidémiologie Respiratoire Intégrative CESP Villejuif France
- Mohamed H. Shamji
- National Heart and Lung Institute Imperial College London UK
- Milan Sova
- Department of Respiratory Medicine and Tuberculosis University Hospital Brno Czech Republic
- Annette Sperl
- Center for Rhinology and Allergology Wiesbaden Germany
- Cristiana Stellato
- Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana” University of Salerno Salerno Italy
- Ana Todo‐Bom
- Imunoalergologia Centro Hospitalar Universitário de Coimbra Faculty of Medicine University of Coimbra Coimbra Portugal
- Peter Valentin Tomazic
- Department of General ORL H&NS Medical University of Graz ENT‐University Hospital Graz Graz Steiermark Austria
- Olivier Vandenplas
- Department of Chest Medicine Centre Hospitalier Universitaire UCL Namur Namur Belgique
- Michiel VanEerd
- Peercode BV Geldermalsen The Netherlands
- Tuula Vasankari
- Fihla, Finnish Lung Association Helsinki Finland
- Frédéric Viart
- ASA ‐ Advanced Solutions Accelerator Jacou France
- Susan Waserman
- Department of Medicine, Clinical Immunology and Allergy McMaster University Hamilton Ontario Canada
- Joao A. Fonseca
- MEDCIDS ‐ Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto Porto Portugal
- Torsten Zuberbier
- Institute of Allergology Charité – Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin Berlin Germany
- DOI
- https://doi.org/10.1002/clt2.12215
- Journal volume & issue
-
Vol. 13,
no. 1
pp. n/a – n/a
Abstract
Abstract MASK‐air®, a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK‐air® is a Good Practice of DG Santé on digitally‐enabled, patient‐centred care. It is also a candidate Good Practice of OECD (Organisation for Economic Co‐operation and Development). MASK‐air® data has enabled novel phenotype discovery and characterisation, as well as novel insights into the management of allergic rhinitis. MASK‐air® data show that most rhinitis patients (i) are not adherent and do not follow guidelines, (ii) use as‐needed treatment, (iii) do not take medication when they are well, (iv) increase their treatment based on symptoms and (v) do not use the recommended treatment. The data also show that control (symptoms, work productivity, educational performance) is not always improved by medications. A combined symptom‐medication score (ARIA‐EAACI‐CSMS) has been validated for clinical practice and trials. The implications of the novel MASK‐air® results should lead to change management in rhinitis and asthma.
Keywords
