This paper concerns the practical application, in a medium city neighborhood in the central-western region of Brazil, of six parameters to support urban vitality: permeability, variety, legibility, versatility, appropriate image, and perceptual wealth, as developed by Bentley & Alcock (1999). The methodological strategy addressed the theoretical framework and the reality of the neighborhood with the support of geotechnologies and urban records. The proposed interventions exercise a combination of urban design instruments, intending to implementing elements of vitality, to reverse the current situation of urban stagnation and social segregation of the place.