Communications Biology (May 2021)
Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis
Abstract
Ferrarini & Lal et al. developed a novel bioinformatic pipeline to explore how SARS-CoV-2 interacts with human respiratory cells using public available host gene expression and viral genome sequence data. Several human genes and proteins were predicted to play a role in the viral life cycle and the host response to SARS-CoV-2 infection.