Emerging Infectious Diseases (Dec 2015)

Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea

  • Wan Beom Park,
  • Ranawaka A.P.M. Perera,
  • Pyoeng Gyun Choe,
  • Eric H.Y. Lau,
  • Seong Jin Choi,
  • June Young Chun,
  • Hong Sang Oh,
  • Kyoung-Ho Song,
  • Ji Hwan Bang,
  • Eu Suk Kim,
  • Hong Bin Kim,
  • Sang Won Park,
  • Nam Joong Kim,
  • Leo Lit Man Poon,
  • Ghazi Kayali,
  • Myoung-don Oh

DOI
https://doi.org/10.3201/eid2112.151421
Journal volume & issue
Vol. 21, no. 12
pp. 2186 – 2189

Abstract

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We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third week of illness. Delayed antibody responses with the neutralization test were associated with more severe disease.

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