mBio
(Apr 2021)
Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation
Shuaiqi Guo,
Tyler D. R. Vance,
Hossein Zahiri,
Robert Eves,
Corey Stevens,
Jan-Hendrik Hehemann,
Silvia Vidal-Melgosa,
Peter L. Davies
Affiliations
Shuaiqi Guo
Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, Ontario, Canada
Tyler D. R. Vance
Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, Ontario, Canada
Hossein Zahiri
Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, Ontario, Canada
Robert Eves
Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, Ontario, Canada
Corey Stevens
Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, Ontario, Canada
Jan-Hendrik Hehemann
Max Planck Institute for Marine Microbiology, Bremen, Germany
Silvia Vidal-Melgosa
Max Planck Institute for Marine Microbiology, Bremen, Germany
Peter L. Davies
ORCiD Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, Ontario, Canada
DOI
https://doi.org/10.1128/mBio.00130-21
Journal volume & issue
Vol. 12,
no. 2
Abstract
Read online
Bacterial adhesins are key virulence factors that are essential for the pathogen-host interaction and biofilm formation that cause most infections. Many of the adhesin-driven cell-cell interactions are mediated by lectins.
WeChat QR code
Close
