Nature Communications (Mar 2023)

Deep learning-enabled segmentation of ambiguous bioimages with deepflash2

  • Matthias Griebel,
  • Dennis Segebarth,
  • Nikolai Stein,
  • Nina Schukraft,
  • Philip Tovote,
  • Robert Blum,
  • Christoph M. Flath

DOI
https://doi.org/10.1038/s41467-023-36960-9
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 14

Abstract

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The signal-to-noise ratio in bioimages is often low, which is problematic for segmentation. Here the authors report a deep learning method, deepflash2, to facilitate the segmentation of ambiguous bioimages through multi-expert annotations and integrated quality assurance.