A new perspective of hypothalamic disease: Shapiro's syndrome

Linan Ren; Xiaokun Gang; Shuo Yang; Meixin Sun; Guixia Wang

doi:10.3389/fneur.2022.911332

Frontiers in Neurology (Jul 2022)

A new perspective of hypothalamic disease: Shapiro's syndrome

Linan Ren,
Xiaokun Gang,
Shuo Yang,
Meixin Sun,
Guixia Wang

Affiliations

Linan Ren: Department of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, China
Xiaokun Gang: Department of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, China
Shuo Yang: Department of Clinical Nutrition, The First Hospital of Jilin University, Changchun, China
Meixin Sun: Department of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, China
Guixia Wang: Department of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, China

DOI: https://doi.org/10.3389/fneur.2022.911332
Journal volume & issue: Vol. 13

Abstract

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Shapiro's syndrome (SS) is characterized by spontaneous periodic hypothermia. It occurs to patients regardless of age or sex. To date, <60 cases have been reported worldwide. Current knowledge of the disease is limited to clinical feature since the pathogenesis and etiology are still controversial. In this review, the clinical characteristics, pathological mechanism, and possible etiology of the syndrome were reviewed to improve the clinical understanding of the disease.

Published in Frontiers in Neurology

ISSN: 1664-2295 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system
Website: https://www.frontiersin.org/journals/neurology/

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Abstract

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