Diagnostics (Nov 2023)

Extracorporeal Membrane Oxygenation (ECMO)-Associated Coagulopathy in Adults

  • Frantzeska Frantzeskaki,
  • Dimitrios Konstantonis,
  • Michail Rizos,
  • Vasileios Kitsinelis,
  • Georgios Skyllas,
  • Ioannis Renieris,
  • Maria Doumani,
  • Vasileios Kolias,
  • Eirini Kefalidi,
  • Dimitrios Angouras,
  • Argyrios Tsantes,
  • Iraklis Tsangaris

DOI
https://doi.org/10.3390/diagnostics13233496
Journal volume & issue
Vol. 13, no. 23
p. 3496

Abstract

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Extracorporeal membrane oxygenation (ECMO) is used for the management of severe respiratory and cardiac failure and as a bridge to achieve definite treatment or transplantation. ECMO-associated coagulopathy (EAC) is a frequent complication leading to high rates of thrombosis or severe haemorrhage, contributing to morbidity and mortality among patients. Understanding the pathophysiology of EAC is substantial for effectively managing patients on ECMO. We analyse the underlying mechanism of EAC and discuss the monitoring of the coagulation profile, combining the viscoelastic point-of-care assays with the conventional coagulation laboratory tests.

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