Journal of Pharmacy and Bioallied Sciences (Aug 2024)
Prevalence of Oral Lichen Planus in Patients with Hypothyroidism Versus Nonhypothyroidism
Abstract
Background: A chronic inflammatory illness known as oral lichen planus (OLP) affects approximately 1–2% of adults, with middle-aged women having a higher prevalence than men. One clinical endocrine condition that primary care doctors frequently see is hypothyroidism. Aim: To compare the prevalence of OLP among individuals with a previous diagnosis of hypothyroidism against those without hypothyroidism. Methods and Materials: A total of 1200 patients were included in this study. As per their medical reports, 600 patients included were found to have hypothyroidism. The rest 600 patients did not have hypothyroidism. All the patients underwent clinical examination and cases of OLP were identified according to the criteria of diagnosis of OLP. Results: Twenty (3.45%) study participants with hypothyroidism were found to have OLP. Eight (1.34%) study participants without hypothyroidism were found to have OLP of 2.37 (confidence interval: 0.91–6.23) and showed that the frequency of lichen planus in study participants with hypothyroidism was 2.37 times greater than that without hypothyroidism. Conclusion: Prevalence of lichen planus in persons with hypothyroidism was greater than that without hypothyroidism.
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