Annals of Clinical and Translational Neurology (Dec 2024)

Emergent responsive neurostimulation in pediatric super‐refractory epilepsia partialis continua

  • Peter N. Hadar,
  • Pranav Nanda,
  • Katherine G. Walsh,
  • John McLaren,
  • Alexandra Geffrey,
  • Mirela Simon,
  • Kristopher Kahle,
  • R. Mark Richardson,
  • Catherine J. Chu

DOI
https://doi.org/10.1002/acn3.52199
Journal volume & issue
Vol. 11, no. 12
pp. 3320 – 3327

Abstract

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Abstract Focal status epilepticus, particularly the motor variant of epilepsia partialis continua (EPC), is a rare condition characterized by near‐continuous, chronic focal motor seizures, and associated with poor outcomes. Medications, including anesthetics, are often unsuccessful. Surgical resection can result in motor deficits. We report a medically complex pediatric case of super‐refractory EPC that was successfully managed with combined focal resection and responsive neuromodulation. This case introduces neuromodulation as a treatment modality for this challenging condition.