Туберкулез и болезни лёгких (Apr 2017)

SPECIFIC FEATURES OF ANTI-TUBERCULOSIS CHEMOTHERAPY TOLERANCE IN THE LIGHT OF PSYCHOLOGICAL STATUS OF PATIENTS

  • N. V. Zolotova,
  • G. V. Baranova,
  • V. V. Streltsov,
  • N. Yu. Kharitonova,
  • A. A. Аkhtyamova,
  • T. R. Bagdasaryan

DOI
https://doi.org/10.21292/2075-1230-2017-95-4-15-19
Journal volume & issue
Vol. 95, no. 4
pp. 15 – 19

Abstract

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Specific features of psychological state were studied in 295 pulmonary tuberculosis patients with satisfactory tolerance to anti-tuberculosis medications and 75 patients poorly tolerating the treatment.Before the treatment start the patients who later demonstrated adverse reactions to treatment were diagnosed with more intense neurotic and hypochondriac personal features, destructive reactions and higher level of emotional tension and frustration – all the above promote dysregulation of the host adaptation. The research demonstrated the need to consider psychological aspects when studying the tolerance to anti-tuberculosis chemotherapy.

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