Caspian Journal of Internal Medicine (Jul 2021)
Unusual presentation of the germinoma: A 26-year-old female
Abstract
Background: Germinoma is a rare lesion found commonly in the pineal and suprasellar regions of the brain. Clinical presentation mainly involves the location and size of the tumor and the patient age. Endocrine abnormalities are the most common symptom. Case Presentation: The patient was a 26-year-old Iranian female who suffered from germinoma for a long time and was referred to Loghman Hakim Hospital for amenorrhea, polyuria, and polydipsia. Despite diagnostic challenges, she was finally diagnosed with suprasellar germinoma after endoscopic transsphenoidal surgery, followed by radiotherapy and medical interventions to complement the surgery. Conclusion: It is important to be able to diagnose the patientchr('39')s problem at an early stage based on their history, hormonal profile, laboratory results and radiological view.