International Journal of General Medicine (Jan 2021)
Evolving Treatment Patterns for Hospitalized COVID-19 Patients in the United States in April 2020–July 2020
Abstract
Xiaozhou Fan,1 Barbara H Johnson,1 Stephen S Johnston,1 Nivesh Elangovanraaj,2 Paul Coplan,1 Rahul Khanna1 1Medical Device Epidemiology and Real World Data Sciences, Johnson & Johnson, New Brunswick, NJ, USA; 2 Mu Sigma Inc, Bangalore, IndiaCorrespondence: Xiaozhou FanMedical Device Epidemiology and Real World Data Sciences, Johnson & Johnson, 410 George St, New Brunswick, NJ 08901, USATel +1 908 208-2625Fax +1 732 524-5242Email [email protected]: We sought to examine the trend (April–July) in the treatment patterns among hospitalized COVID-19 patients using the Premier Healthcare Database (PHD). In the analysis, we identified 53,264 patients from 302 hospitalsthat continuously provided inpatient data from April 1, 2020 to July 31, 2020 to the PHD, a nationwide, population-based multihospital research database in the US. We used generalized estimating equations (GEE) models to assess changes in the proportion of therapies used during the study period. After adjusting for patient and provider factors, a decline in hydroxychloroquine and an increase in azithromycin and dexamethasone were observed among COVID-19 patients during the 4-month study period.Keywords: COVID-19, hospitalization, treatment pattern
