World Journal of Surgical Oncology (Mar 2009)

Synchronous colorectal adenocarcinoma and gastrointestinal stromal tumor in Meckel's diverticulum; an unusual association

  • Masmanidou Maria,
  • Tzeveleki Ioanna,
  • Grigoriou Marios,
  • Baka Sofia,
  • Anthimidis George,
  • Levva Sofia,
  • Efthimiadis Christopher,
  • Kosmidis Christopher,
  • Zaramboukas Thomas,
  • Basdanis Georgios

DOI
https://doi.org/10.1186/1477-7819-7-33
Journal volume & issue
Vol. 7, no. 1
p. 33

Abstract

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Abstract Background Coexistence of gastrointestinal stromal tumor with synchronous or metachronous colorectal cancer represents a phenomenon with increasing number of relative reports in the last 5 years. Synchronous occurence of GISTs with other gastrointestinal tumors of different histogenesis presents a special interest. We herein report a case of GIST in Meckel's diverticulum synchronous with colorectal adenocarcinoma. Case presentation A 69 year old man, presented with abdominal distension and anal bleeding on defecation. Colonoscopy revealed colorectal cancer and a low anterior resection was performed, during which a tumor in Meckel's diverticulum was discovered. Histologic examination revealed GIST in Meckel's diverticulum and a rectosigmoid adenocarcinoma. Conclusion Whenever GIST is encountered, the surgeon should be alert to recognize a possible coexistent tumor with different histological origin. Correct diagnosis of synchronous tumors of different origin is the cornerstone of treatment.