Nature Communications (Dec 2022)

Bond-selective intensity diffraction tomography

  • Jian Zhao,
  • Alex Matlock,
  • Hongbo Zhu,
  • Ziqi Song,
  • Jiabei Zhu,
  • Biao Wang,
  • Fukai Chen,
  • Yuewei Zhan,
  • Zhicong Chen,
  • Yihong Xu,
  • Xingchen Lin,
  • Lei Tian,
  • Ji-Xin Cheng

DOI
https://doi.org/10.1038/s41467-022-35329-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

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The authors introduce Bond-selective Intensity Diffraction Tomography, a computational mid-infrared photothermal microscopy technique based on a standard bright-field microscope and an add-on pulsed light source. It recovers both mid-infrared spectra and bond-selective 3D refractive index maps based on intensity-only measurements.