The Interaction Between Non-Coding RNAs and Calcium Binding Proteins

Soudeh Ghafouri-Fard; Jamal Majidpoor; Hamed Shoorei; Bashdar Mahmud Hussen; Bashdar Mahmud Hussen; Hazha Hadayat Jamal; Aria Baniahmad; Mohammad Taheri; Mohammad Taheri; Majid Mokhtari

doi:10.3389/fonc.2022.848376

Frontiers in Oncology (Mar 2022)

The Interaction Between Non-Coding RNAs and Calcium Binding Proteins

Soudeh Ghafouri-Fard,
Jamal Majidpoor,
Hamed Shoorei,
Bashdar Mahmud Hussen,
Bashdar Mahmud Hussen,
Hazha Hadayat Jamal,
Aria Baniahmad,
Mohammad Taheri,
Mohammad Taheri,
Majid Mokhtari

Affiliations

Soudeh Ghafouri-Fard: Department of Medical Genetics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Jamal Majidpoor: Department of Anatomy, Faculty of Medicine, Infectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran
Hamed Shoorei: Department of Anatomical Sciences, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran
Bashdar Mahmud Hussen: Department of Pharmacognosy, College of Pharmacy, Hawler Medical University, Erbil, Iraq
Bashdar Mahmud Hussen: Center of Research and Strategic Studies, Lebanese French University, Erbil, Iraq
Hazha Hadayat Jamal: Department of Biology, College of Education, Salahaddin University-Erbil, Erbil, Iraq
Aria Baniahmad: Institute of Human Genetics, Jena University Hospital, Jena, Germany
Mohammad Taheri: Institute of Human Genetics, Jena University Hospital, Jena, Germany
Mohammad Taheri: Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Majid Mokhtari: Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

DOI: https://doi.org/10.3389/fonc.2022.848376
Journal volume & issue: Vol. 12

Abstract

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Calcium binding proteins (CBP) are a group of proteins mediating the effects of calcium on cellular functions. These proteins can regulate calcium levels inside the cells and contribute in several cellular functions through transporting this ion across cell membranes or decoding related signals. Recent studies have shown that several non-coding RNAs interact with CBPs to affect their expression or activity. The interactions between these transcripts and CBPs have implications in the pathoetiology of human disorders, including both neoplastic and non-neoplastic conditions. In the current review, we describe the interactions between three classes of non-coding RNAs (long non-coding RNAs, circular RNAs, and microRNAs) and a number of CBPs, particularly CAB39, S100A1, S100A4, S100A7 and S100P. This kind of interaction has been verified in different pathological contexts such as drug-induced cardiotoxicity, osteoblasts cytotoxicity, acute lung injury, myocardial ischemia/reperfusion injury, proliferative diabetic retinopathy, glomerulonephritis, as well as a wide array of neoplastic conditions.

Published in Frontiers in Oncology

ISSN: 2234-943X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.frontiersin.org/journals/oncology/

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Abstract

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