Nivolumab induced vitiligo-like depigmentation in metastatic acral lentiginous melanoma

Abstract

Melanoma is an uncommon malignancy in Indian subcontinent. Dermoscopy of cutaneous metastases of malignant melanoma has been rarely reported. Immune checkpoint inhibitors are increasingly being used for management of metastatic melanoma. They are associated with frequent cutaneous adverse events. Few of the cutaneous adverse events are associated with better prognosis for melanoma. We report a rare case of metastatic acral lentiginous melanoma for rarity of dermoscopic findings of cutaneous metastases and adverse effect due to immune checkpoint inhibitor.

Keywords

• dermoscopy
• immune checkpoint inhibitors
• malignant melanoma
• nivolumab
• vitiligo-like depigmentation